Semaglutide Dosage Calculator
Calculate your exact semaglutide dose in units and ml for compounded vials. Works for any concentration.
Common: 2mg, 5mg, 10mg vials
What is Semaglutide?
Semaglutide is a GLP-1 receptor agonist originally developed for type 2 diabetes management. It mimics the natural hormone GLP-1, which regulates blood sugar levels and appetite. It is now widely used for weight management under the brand names Ozempic (for diabetes) and Wegovy (for weight loss).
Semaglutide works by slowing gastric emptying, reducing appetite, and improving insulin sensitivity. Clinical trials have shown average weight loss of 15 to 17% of body weight over 68 weeks at the 2.4 mg weekly dose.
Compounded semaglutide is available as a lyophilized powder that must be reconstituted with bacteriostatic water before injection. This calculator helps you determine the exact volume to draw for your prescribed dose.
Standard Titration Schedule
Semaglutide is always started at a low dose and gradually increased to minimize side effects.
How to Use This Calculator
- 1.Enter your vial size in milligrams. This is the total amount of semaglutide in your vial (printed on the label).
- 2.Enter how much bacteriostatic water you added (or plan to add) during reconstitution.
- 3.Select or type your weekly dose. If you are just starting, use 0.25 mg and follow the titration schedule above.
- 4.The calculator will show you the exact number of units to draw on your insulin syringe.
Frequently Asked Questions
What is the starting dose for semaglutide?
The standard starting dose is 0.25 mg once per week for the first 4 weeks. This allows your body to adjust and minimizes gastrointestinal side effects like nausea. Never start at a higher dose, even if you are eager to see results faster.
How fast should I increase my dose?
The standard titration schedule increases the dose every 4 weeks: 0.25 mg, then 0.5 mg, then 1 mg, then 1.7 mg, up to a maximum of 2.4 mg per week. Some people find they get sufficient results at lower doses and do not need to titrate all the way up.
When should I inject semaglutide?
Semaglutide is injected once weekly, on the same day each week. You can inject at any time of day, with or without food. Most people pick a consistent day (like Sunday or Monday) to make it easy to remember.
Where do I inject semaglutide?
Inject subcutaneously in the abdomen, thigh, or upper arm. Rotate injection sites to avoid irritation. The abdomen is the most common and usually the easiest for self-injection.
What are common side effects?
The most common side effects are nausea, vomiting, diarrhea, and constipation, especially during dose increases. These usually improve as your body adjusts. Eating smaller meals, staying hydrated, and avoiding fatty foods can help manage nausea.
What is the difference between compounded and brand-name semaglutide?
Brand-name semaglutide (Ozempic, Wegovy) comes in pre-filled injection pens at fixed concentrations. Compounded semaglutide comes as a lyophilized powder that you reconstitute yourself, which is why a dosage calculator is helpful. The active molecule is the same.
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