TB-500 Dosage Calculator
Get your personalized TB-500 loading and maintenance doses based on your body weight, injury type, and experience level.
What is TB-500?
TB-500 is a synthetic version of a naturally occurring 43-amino-acid peptide fragment of Thymosin Beta-4 (Tβ4). Thymosin Beta-4 is a protein produced by the thymus gland and found in virtually all human cells. TB-500 replicates the active region of Tβ4 responsible for tissue repair, cell migration, and anti-inflammatory signaling.
The primary mechanism of TB-500 is the upregulation of actin, a cell-building protein that plays a critical role in cell structure, movement, and division. By promoting actin production, TB-500 accelerates the migration of endothelial cells and keratinocytes to injury sites, which speeds up wound healing, reduces inflammation, and supports the formation of new blood vessels.
TB-500 has been studied for its effects on tendons, ligaments, muscles, skin, and cardiac tissue. Unlike many peptides that act locally, TB-500 has a systemic effect due to its low molecular weight and unique molecular structure, which allows it to travel through tissues over long distances. This makes it a popular choice for both acute injuries and chronic repair. Many researchers stack TB-500 with BPC-157 for combined systemic and local healing. For detailed dosing charts, see our TB-500 dosage guide.
How to Use This Calculator
- 1.Enter your body weight in kilograms or pounds. While TB-500 dosing is less weight-dependent than some peptides, your weight helps contextualize the protocol.
- 2.Select your phase. The loading phase uses higher doses twice per week to saturate tissues. The maintenance phase uses a lower dose once per week to sustain healing.
- 3.Choose your injury type. Joint injuries use a slightly higher dose, while general recovery uses a lower dose. Tendon and muscle injuries fall in between.
- 4.Select your experience level. Beginners start at the lower end of the dose range, while advanced users can use higher therapeutic doses.
- 5.Click "Calculate My Dose" to get your personalized protocol with per-dose amount, frequency, weekly total, and cycle length.
TB-500 Dosage Quick Reference
Frequently Asked Questions
What is the standard TB-500 dosing protocol?
The most common TB-500 protocol starts with a loading phase of 2 to 2.5 mg injected twice per week for 4 to 6 weeks, followed by a maintenance phase of 1 to 2 mg once per week for another 4 to 8 weeks. The loading phase front-loads the peptide to saturate tissues, while maintenance keeps levels elevated for continued repair.
How long should I run a TB-500 cycle?
A full TB-500 cycle typically lasts 8 to 14 weeks total: 4 to 6 weeks of loading followed by 4 to 8 weeks of maintenance. After completing a cycle, most users take at least 4 weeks off before starting another. Chronic or severe injuries may benefit from longer maintenance periods.
Where should I inject TB-500?
TB-500 is injected subcutaneously, typically in the abdominal area, similar to insulin. Unlike BPC-157, TB-500 does not need to be injected near the injury site because it acts systemically. The peptide upregulates actin throughout the body, so the injection location does not affect which tissues benefit.
Can I stack TB-500 with BPC-157?
Yes. TB-500 and BPC-157 are frequently stacked together for injury recovery. They work through different mechanisms: BPC-157 promotes angiogenesis and local tissue repair, while TB-500 upregulates actin for cell migration and tissue remodeling. Many users inject both peptides during the same protocol for a synergistic healing effect.
What are the side effects of TB-500?
TB-500 is generally well tolerated. Some users report temporary head rushes, mild nausea, or slight lethargy after injection. Redness or irritation at the injection site can occur but is usually minor. Serious adverse effects are rare in published research, though long-term human safety data remains limited.
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