TB-500 (Thymosin Beta-4) is one of the most effective peptides for healing injuries, but dosing is confusing. Too little won't deliver results; too much wastes expensive product. This evidence-based TB-500 dosage chart shows exactly how much to use for tendonitis, muscle tears, joint injuries, and recovery.
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TB-500 Dosage Chart: Quick Reference
LOADING PHASE (Weeks 1-4): • Injury Healing: 5-10mg per week (split into 2-3 doses) • Severe injury (torn tendon/muscle): 10mg per week • Mild injury (tendonitis, strain): 5-7.5mg per week • Frequency: 2-3 injections per week (e.g., Monday/Thursday or Mon/Wed/Fri)
MAINTENANCE PHASE (Weeks 5+): • Dosage: 2.5-5mg per week (single dose or split) • Frequency: Once or twice per week • Duration: 4-8 weeks total, then reassess
PREVENTION/RECOVERY: • Dosage: 2.5mg per week • Frequency: Once weekly • Use case: Athletes preventing injury or speeding general recovery
TB-500 Dosage by Injury Type
Different injuries respond to different dosing strategies:
Tendonitis (Tennis Elbow, Achilles, Rotator Cuff)
• Loading: 5-7.5mg/week for 4 weeks • Maintenance: 2.5-5mg/week for 4-6 weeks • Injection site: Subcutaneous (abdomen) or near injury • Expected results: Noticeable improvement in 2-3 weeks
Muscle Tears or Strains
• Loading: 7.5-10mg/week for 4 weeks • Maintenance: 5mg/week for 4 weeks • Injection site: Subcutaneous, close to injury if possible • Expected results: Faster recovery, reduced scar tissue
Joint Injuries (Knee, Shoulder, Hip)
• Loading: 5-10mg/week for 4-6 weeks • Maintenance: 2.5-5mg/week for 4-8 weeks • Stack with: BPC-157 for localized healing • Expected results: Reduced inflammation, improved mobility
Post-Surgery Recovery
• Dosage: 5mg/week starting 1 week post-op • Duration: 6-8 weeks • Note: Consult surgeon before use; TB-500 accelerates tissue repair
How to Inject TB-500: Step-by-Step
Reconstitution: 1. TB-500 typically comes in 5mg vials 2. Add 2ml bacteriostatic water for easy dosing (1ml = 2.5mg) 3. Inject water slowly down the vial side, don't shake 4. Gently swirl until fully dissolved 5. Store in refrigerator (good for 30 days)
Injection: 1. Draw desired dose (e.g., 0.5ml for 1.25mg, 1ml for 2.5mg) 2. Subcutaneous injection (pinch fat, inject at 45° angle) 3. Preferred sites: abdomen, thigh, or near injury 4. Rotate injection sites to prevent scar tissue 5. Insulin syringes (0.5ml or 1ml, 29-31 gauge) work best
TB-500 Injection Frequency: Does Timing Matter?
TB-500 has a long half-life (~7-10 days), so precise timing isn't critical, but consistency matters:
• 2x per week: Monday/Thursday or Tuesday/Friday (most common) • 3x per week: Mon/Wed/Fri (higher total dose weeks) • 1x per week: Maintenance phase only
Does injection timing affect results? No strong evidence suggests morning vs. evening makes a difference. Some users inject post-workout for perceived synergy, but this isn't scientifically proven. Consistency is more important than timing.
TB-500 Dosage for Athletes vs. Injury Recovery
Injury Recovery (Priority: Healing): • Aggressive loading phase: 10mg/week • Targeted to specific injury • Short-term use (8-12 weeks)
Athletic Performance/Prevention (Priority: Recovery): • Conservative dosing: 2.5-5mg/week • General systemic benefits • Can cycle on/off throughout season • Helps prevent overuse injuries
Bodybuilding (Rare Use Case): TB-500 isn't primarily a muscle-building peptide. It's for injury prevention during heavy training. If this is your goal, 2.5mg/week year-round is more cost-effective than higher doses.
Common TB-500 Dosing Mistakes
1. Skipping the Loading Phase Many users start at 2.5mg/week and wonder why it's not working. The loading phase (5-10mg/week) builds up serum levels necessary for healing. Don't skip it.
2. Stopping Too Soon TB-500 works slowly. Many injuries need 6-8 weeks minimum. Stopping at 4 weeks because you 'feel better' often leads to relapse.
3. Using Expired or Improperly Stored Product Reconstituted TB-500 lasts ~30 days refrigerated. After that, potency drops. Don't reconstitute entire supply at once unless you'll use it within a month.
4. Injecting Only at Injury Site TB-500 works systemically. It doesn't need to be injected directly into the injury. Subcutaneous (belly fat) is just as effective and less painful.
5. Not Combining with BPC-157 For serious injuries, TB-500 (systemic healing) + BPC-157 (localized healing) is the gold standard stack. Using one without the other leaves results on the table.
TB-500 + BPC-157 Stack Dosing
The most popular peptide stack for injury healing:
Loading Phase (4 weeks): • TB-500: 5-10mg/week (2-3x weekly) • BPC-157: 250-500mcg/day (daily injections)
Maintenance Phase (4-6 weeks): • TB-500: 2.5-5mg/week (1-2x weekly) • BPC-157: 250mcg/day or stop
Why stack them? • TB-500 = systemic healing (tendons, ligaments, muscles) • BPC-157 = localized healing (accelerates repair at injury site) • Together = faster recovery + less scar tissue
For collagen remodeling support during healing, consider adding GHK-Cu to the stack.
Frequently Asked Questions
How much TB-500 should I take per week?
For injury healing: 5-10mg/week during loading phase (weeks 1-4), then 2.5-5mg/week maintenance. For general recovery: 2.5mg/week is sufficient.
Can I inject TB-500 every day?
You can, but it's unnecessary and wasteful. TB-500 has a long half-life, so 2-3x per week is optimal. Daily injections don't improve results and cost significantly more.
Where should I inject TB-500?
Subcutaneous injection in the abdomen is easiest and most common. You can inject near the injury site, but systemic (belly/thigh) injections work just as well since TB-500 circulates throughout the body.
How long does TB-500 take to work?
Most users notice improvement in 2-4 weeks with proper loading dosing (5-10mg/week). Severe injuries may take 6-8 weeks. If you see no improvement after 6 weeks, dosing may be too low or the injury may require medical intervention.
Is 2.5mg of TB-500 per week enough?
For maintenance or prevention, yes. For active injury healing, 2.5mg/week is too low. You need 5-10mg/week during the loading phase to build sufficient serum levels.
Can I take TB-500 long-term?
TB-500 is typically used for 8-12 week cycles, then discontinued once the injury heals. Long-term daily use isn't well-studied and is unnecessarily expensive. Some athletes use 2.5mg/week year-round for injury prevention.
The Bottom Line
TB-500 dosing follows a loading/maintenance approach: 5-10mg/week for 4 weeks, then 2.5-5mg/week. Clinical data and anecdotal success support this protocol.
Don't under-dose during the critical first month, and give the peptide 6-8 weeks minimum. For serious injuries, stack with BPC-157 for maximum healing. Source pharmaceutical-grade TB-500 and store reconstituted vials properly.
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